Zip Code: 311121
Tel: 0571-89081561
Fax: 0571-89081566
Site: www.jiandu99.com.cn
E-mail: info@cheminspire.com
Service
Our Technologies Include:
² Asymmetric Synthesis Technology
ü Enzymatic transformation(Chiral amine, Chiral alcohol, Un-nature amino acid)
ü Asymmetric hydrogenation
ü Chiral auxiliary (Chiral sulfinamide, Evan’s Auxiliary etc) asymmetric synthesis
ü Chemical Resolution with chiral acid or amine
² Coupling Technology
Suzuki coupling, Buchwald reaction, Sonogashira reaction, Negishi reaction, Heck reaction , Stille reaction, Cu Nickel catalyzed C-C, C-N, C-O coupling are widely applied in our research and production.
² Grignard Reaction
With extensive experience, we can carry out up to 10000L Grignard reaction
Our Service Includes:
Custom Synthesis Service
- Medicinal chemistry scaffold and building blocks
- Scale-up of selected compounds for further evaluation
- Reference compound, assay standard, and metabolite
- Key and advanced intermediates
- Synthetic pathway design, evaluation and route scouting
Process R & D and Production
- Research and development of chemical processes suitable for the synthesis of preclinical and phase I/II study materials from the original medicinal chemistry route
- Process improvement of existing chemical process
- Validation of process technical package provided by customers
- Production of non-GMP material and advanced intermediates up to hundreds of kilograms